{"id":267,"date":"2017-09-11T12:41:19","date_gmt":"2017-09-11T04:41:19","guid":{"rendered":"https:\/\/credevo.com\/articles\/\/?p=267"},"modified":"2021-09-20T18:32:01","modified_gmt":"2021-09-20T10:32:01","slug":"acute-unilateral-vestibulopathy-a-clinical-trial-feasibility","status":"publish","type":"post","link":"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/","title":{"rendered":"Acute Unilateral Vestibulopathy &#8211; A Clinical Trial Feasibility"},"content":{"rendered":"\n<p>Acute vestibulopathy is characterized by an acute or subacute onset of vertigo, dizziness, or imbalance with or without ocular motor, sensory, postural or autonomic symptoms, and signs, and can last for seconds to up to several days.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"548\" src=\"https:\/\/credevo.com\/articles\/\/wp-content\/uploads\/2017\/10\/acute_unilateral_vestibulopathy_clinical_trial_feasibility_credevo-1024x548.jpg\" alt=\"acute_unilateral_vestibulopathy_clinical_trial_feasibility_credevo\" class=\"wp-image-287\" srcset=\"https:\/\/credevo.com\/articles\/wp-content\/uploads\/2017\/10\/acute_unilateral_vestibulopathy_clinical_trial_feasibility_credevo-1024x548.jpg 1024w, https:\/\/credevo.com\/articles\/wp-content\/uploads\/2017\/10\/acute_unilateral_vestibulopathy_clinical_trial_feasibility_credevo-300x161.jpg 300w, https:\/\/credevo.com\/articles\/wp-content\/uploads\/2017\/10\/acute_unilateral_vestibulopathy_clinical_trial_feasibility_credevo-768x411.jpg 768w, https:\/\/credevo.com\/articles\/wp-content\/uploads\/2017\/10\/acute_unilateral_vestibulopathy_clinical_trial_feasibility_credevo-732x392.jpg 732w, https:\/\/credevo.com\/articles\/wp-content\/uploads\/2017\/10\/acute_unilateral_vestibulopathy_clinical_trial_feasibility_credevo-1140x610.jpg 1140w, https:\/\/credevo.com\/articles\/wp-content\/uploads\/2017\/10\/acute_unilateral_vestibulopathy_clinical_trial_feasibility_credevo.jpg 1920w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">What is Acute Unilateral Vestibulopathy?<\/h2>\n\n\n\n<p>Normal vestibular end organs generate an equal resting-firing frequency of the axons, which is the same on both sides under static conditions. An acute unilateral vestibulopathy leads to a vestibular tone imbalance.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What are the symptoms of Acute Unilateral Vestibulopathy?<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Acute onset of spinning vertigo and oscillopsia are the hallmarks of acute unilateral vestibulopathy. In addition, the patients have a postural imbalance, a tendency to fall to the affected side, and suffer from nausea and vomiting.<\/li><li>Key signs and symptoms are acute onset of spinning vertigo, postural imbalance, and nausea as well as horizontal rotatory nystagmus beating towards the non-affected side, a pathological head-impulse test, and no evidence for the central vestibular or ocular motor dysfunction.<\/li><li>Acute unilateral vestibulopathy is defined by the patient&#8217;s history and clinical examination and, in unclear cases, laboratory examinations.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What is the prevalence of Acute Unilateral Vestibulopathy (AUV)?<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Acute Unilateral Vestibulopathy is widely considered a rare condition.<\/li><li>Currently, there\u2019s not enough data on the prevalence of Acute Unilateral Vestibulopathy. For a year, the incidence of AUV between 3.5 and 15.5 per 100,000 persons was described. Acute Unilateral Vestibulopathy accounts for about 8% of patients with vertigo, which also happens to children.<\/li><li>The age distribution plateaus are between 40 and 50 years, and there is no gender difference. The recurrence rate varies between 1.9% and 10.7%.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What are available treatments for Acute Unilateral Vestibulopathy?<\/h2>\n\n\n\n<p>The management of acute unilateral vestibulopathy involves<\/p>\n\n\n\n<ol class=\"wp-block-list\"><li>Symptomatic treatment with antivertiginous drugs (eg, meclizine, dimenhydrinate, scopolamine, or in severe cases benzodiazepines) to attenuate vertigo, dizziness, and nausea\/vomiting,<\/li><li>Causal treatment with corticosteroids to improve recovery of peripheral vestibular function; and<\/li><li>Physical therapy (vestibular exercises and balance training) to improve central vestibular compensation.<\/li><\/ol>\n\n\n\n<p>Vestibular Physical Therapy is a gradual program of physical exercise under the supervision of a physiotherapist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Clinical trials in Acute Unilateral Vestibulopathy?<\/h2>\n\n\n\n<p>Interestingly, a <a href=\"https:\/\/clinicaltrials.gov\/ct2\/results?cond=Acute+Unilateral+Vestibulopathy&amp;term=&amp;cntry1=&amp;state1=&amp;recrs=\">search on clinicaltrials.gov<\/a> does not come up with many clinical trials in Acute Unilateral Vestibulopathy. There are only two clinical trials listed on clinicaltrials.gov and both of these are in Europe.<\/p>\n\n\n\n<ol class=\"wp-block-list\"><li><a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT03110458?cond=Acute+Unilateral+Vestibulopathy&amp;rank=1\">Efficacy of SENS-111 in Patients Suffering From Acute Unilateral Vestibulopathy<\/a><\/li><li><a href=\"https:\/\/clinicaltrials.gov\/ct2\/show\/NCT02912182?cond=Acute+Unilateral+Vestibulopathy&amp;rank=2\">Acute Unilateral Vestibulopathy and Corticosteroid Treatment<\/a><\/li><\/ol>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/clinicaltrials.gov\/ct2\/results\/map?cond=Acute+Unilateral+Vestibulopathy&amp;map=\"><img loading=\"lazy\" decoding=\"async\" width=\"801\" height=\"445\" src=\"https:\/\/credevo.com\/articles\/\/wp-content\/uploads\/2017\/10\/acute_unilateral_vestibulopathy_clinical_trials_worldwide_credevo.png\" alt=\"acute_unilateral_vestibulopathy_clinical_trials_worldwide_credevo\" class=\"wp-image-290\" srcset=\"https:\/\/credevo.com\/articles\/wp-content\/uploads\/2017\/10\/acute_unilateral_vestibulopathy_clinical_trials_worldwide_credevo.png 801w, https:\/\/credevo.com\/articles\/wp-content\/uploads\/2017\/10\/acute_unilateral_vestibulopathy_clinical_trials_worldwide_credevo-300x167.png 300w, https:\/\/credevo.com\/articles\/wp-content\/uploads\/2017\/10\/acute_unilateral_vestibulopathy_clinical_trials_worldwide_credevo-768x427.png 768w, https:\/\/credevo.com\/articles\/wp-content\/uploads\/2017\/10\/acute_unilateral_vestibulopathy_clinical_trials_worldwide_credevo-732x407.png 732w\" sizes=\"(max-width: 801px) 100vw, 801px\" \/><\/a><\/figure>\n\n\n\n<p>However, including the term &#8220;vestibular neuritis&#8221; in the <a href=\"https:\/\/clinicaltrials.gov\/ct2\/results?cond=Vestibular+Neuritis&amp;term=&amp;cntry=&amp;state=&amp;city=&amp;dist=\">search indicates 20 clinical trials<\/a> in this segment. It can be noted that sometimes, vestibular neuritis has been used to indicate Acute Unilateral Vestibulopathy.<\/p>\n\n\n\n<p>In the European clinical trial register, there were 4 clinical trials found in the search. These clinical trials include found in clinicaltrials.gov as well as the famous BETAVEST clinical trial.<\/p>\n\n\n\n<p>BETAVEST clinical trial&nbsp;involved investigations on&nbsp;the effects of betahistine on central compensation in acute unilateral vestibulopathy (betahistine-dihydrochloride, 48 mg thrice a day, vs placebo; the BETAVEST trial), which focuses on postural imbalance, spontaneous nystagmus, and functional impairment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Clinical trial feasibility in Acute Unilateral Vestibulopathy<\/h2>\n\n\n\n<p>Clinical trial feasibility for Acute Unilateral Vestibulopathy has been performed on Credevo.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Phase of the trial<\/h3>\n\n\n\n<p>This clinical trial was a phase 2\/3 trial in adults with Acute Unilateral Vestibulopathy (AUV).<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Investigational drug<\/h3>\n\n\n\n<p>The drug under investigation in this clinical trial was an antagonist of the histamine H4 receptor. It was developed as a potential novel therapy for patients suffering from AUV with the aim of improving associated symptoms without preventing long-term recovery.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Previous data<\/h3>\n\n\n\n<p>Previous data included Phase 1 data from 4 clinical studies with safety established. The drug was well tolerated and the maximally tolerated dose was not reached. No dose-dependent adverse event was observed. There were no cardiac or mutagenic effects.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Sites and region<\/h3>\n\n\n\n<p>Total 3 sites from Australia were required in this clinical trial.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Therapeutic area<\/h3>\n\n\n\n<p>Investigators and sites with capability and expertise in neurology and otolaryngology have been explored for this clinical trial.<\/p>\n\n\n\n<hr class=\"wp-block-separator\"\/>\n\n\n\n<h3 class=\"wp-block-heading\">Contact investigators from this feasibility assessment or Get any other support for conducting such rare disease clinical trials<\/h3>\n\n\n\n<p>Would you like to contact these investigators and assess feasibility with them for your clinical trial? or Do you need any other support for conducting such clinical trials?<\/p>\n\n\n\n<p>Now, it&#8217;s very easy to do so.<\/p>\n\n\n\n<p>Just provide your requirement details &amp; email below. Don\u2019t worry, your email will not be published or shared.<\/p>\n\n\n<div class=\"wpforms-container wpforms-container-full\" id=\"wpforms-4816\"><form id=\"wpforms-form-4816\" class=\"wpforms-validate wpforms-form\" data-formid=\"4816\" method=\"post\" enctype=\"multipart\/form-data\" action=\"\/articles\/wp-json\/wp\/v2\/posts\/267\" data-token=\"72b3a264fcdcc7fc930ff220ae7a7ed6\" data-token-time=\"1775723738\"><noscript class=\"wpforms-error-noscript\">Please enable JavaScript in your browser to complete this form.<\/noscript><div class=\"wpforms-field-container\"><div id=\"wpforms-4816-field_3-container\" class=\"wpforms-field wpforms-field-textarea\" data-field-id=\"3\"><label class=\"wpforms-field-label\" for=\"wpforms-4816-field_3\">Provide your requirement details here <span class=\"wpforms-required-label\">*<\/span><\/label><textarea id=\"wpforms-4816-field_3\" class=\"wpforms-field-medium wpforms-field-required\" name=\"wpforms[fields][3]\" required><\/textarea><\/div><div id=\"wpforms-4816-field_1-container\" class=\"wpforms-field wpforms-field-email\" data-field-id=\"1\"><label class=\"wpforms-field-label\" for=\"wpforms-4816-field_1\">Provide Your Work Email <span class=\"wpforms-required-label\">*<\/span><\/label><input type=\"email\" id=\"wpforms-4816-field_1\" class=\"wpforms-field-medium wpforms-field-required\" name=\"wpforms[fields][1]\" spellcheck=\"false\" required><\/div><\/div><!-- .wpforms-field-container --><div class=\"wpforms-field wpforms-field-hp\"><label for=\"wpforms-4816-field-hp\" class=\"wpforms-field-label\">Comment<\/label><input type=\"text\" name=\"wpforms[hp]\" id=\"wpforms-4816-field-hp\" class=\"wpforms-field-medium\"><\/div><div class=\"wpforms-recaptcha-container wpforms-is-recaptcha wpforms-is-recaptcha-type-v2\" ><div class=\"g-recaptcha\" data-sitekey=\"6LeaQRYTAAAAAPo7U8jnZJBUndxcS3f0E3Vijb2k\"><\/div><input type=\"text\" name=\"g-recaptcha-hidden\" class=\"wpforms-recaptcha-hidden\" style=\"position:absolute!important;clip:rect(0,0,0,0)!important;height:1px!important;width:1px!important;border:0!important;overflow:hidden!important;padding:0!important;margin:0!important;\" data-rule-recaptcha=\"1\"><\/div><div class=\"wpforms-submit-container\" ><input type=\"hidden\" name=\"wpforms[id]\" value=\"4816\"><input type=\"hidden\" name=\"page_title\" value=\"\"><input type=\"hidden\" name=\"page_url\" value=\"https:\/\/credevo.com\/articles\/wp-json\/wp\/v2\/posts\/267\"><input type=\"hidden\" name=\"url_referer\" value=\"\"><button type=\"submit\" name=\"wpforms[submit]\" id=\"wpforms-submit-4816\" class=\"wpforms-submit\" data-alt-text=\"Submitting your request...\" data-submit-text=\"Yes, please send me details\" aria-live=\"assertive\" value=\"wpforms-submit\">Yes, please send me details<\/button><\/div><\/form><\/div>  <!-- .wpforms-container -->\n\n\n\n<p><em>For other details,&nbsp;contact us at <a href=\"mailto:helpdesk@credevo.com\" target=\"_blank\" rel=\"noreferrer noopener\">helpdesk@credevo.com<\/a>.<\/em><\/p>\n\n\n\n<hr class=\"wp-block-separator\"\/>\n\n\n\n<h3 class=\"wp-block-heading\">References<\/h3>\n\n\n\n<ol class=\"wp-block-list\"><li id=\"ref-1\">Acute vestibulopathy. Strupp M1, Arbusow V.;&nbsp;Curr Opin Neurol. 2001 Feb;14(1):11-20.<\/li><li id=\"ref-2\">Strupp, Michael &amp; Magnusson, M\u00e5ns. (2015). Acute Unilateral Vestibulopathy. Neurologic clinics. 33. 669-685. 10.1016\/j.ncl.2015.04.012.<\/li><li id=\"ref-3\"><a href=\"http:\/\/www.neurocular.com\/node\/152\">Acute unilateral vestibulopathy (\u201cvestibular neuritis\u201d)<\/a><\/li><li id=\"ref-4\"><a href=\"https:\/\/credevo.com\/myzone\/submit_feasibility?project_id=19\">Clinical trial feasibility in Acute Unilateral Vestibulopathy on Credevo<\/a><\/li><\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Acute vestibulopathy is characterized by an acute or subacute onset of vertigo, dizziness, or imbalance with or without ocular motor, sensory, postural or autonomic symptoms, and signs, and can last for seconds to up to several days. What is Acute Unilateral Vestibulopathy? Normal vestibular end organs generate an equal resting-firing frequency of the axons, which [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":287,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"cybocfi_hide_featured_image":"","footnotes":""},"categories":[566,567],"tags":[60,266,82],"class_list":["post-267","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-clinical-development","category-feasibility","tag-australia","tag-clinical-trial-feasibility","tag-tga"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v23.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Acute Unilateral Vestibulopathy - A Clinical Trial Feasibility | Credevo Articles<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Acute Unilateral Vestibulopathy - A Clinical Trial Feasibility | Credevo Articles\" \/>\n<meta property=\"og:description\" content=\"Acute vestibulopathy is characterized by an acute or subacute onset of vertigo, dizziness, or imbalance with or without ocular motor, sensory, postural or autonomic symptoms, and signs, and can last for seconds to up to several days. What is Acute Unilateral Vestibulopathy? Normal vestibular end organs generate an equal resting-firing frequency of the axons, which [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/\" \/>\n<meta property=\"og:site_name\" content=\"Credevo Articles\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/credevo\" \/>\n<meta property=\"article:published_time\" content=\"2017-09-11T04:41:19+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2021-09-20T10:32:01+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/credevo.com\/articles\/wp-content\/uploads\/2017\/10\/acute_unilateral_vestibulopathy_clinical_trial_feasibility_credevo.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1920\" \/>\n\t<meta property=\"og:image:height\" content=\"1028\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Feasibility Team\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@gocredevo\" \/>\n<meta name=\"twitter:site\" content=\"@gocredevo\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Feasibility Team\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/#article\",\"isPartOf\":{\"@id\":\"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/\"},\"author\":{\"name\":\"Feasibility Team\",\"@id\":\"https:\/\/credevo.com\/articles\/#\/schema\/person\/eaf79e204cf3f6b11d8925cdd7adb3ed\"},\"headline\":\"Acute Unilateral Vestibulopathy &#8211; A Clinical Trial Feasibility\",\"datePublished\":\"2017-09-11T04:41:19+00:00\",\"dateModified\":\"2021-09-20T10:32:01+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/\"},\"wordCount\":774,\"publisher\":{\"@id\":\"https:\/\/credevo.com\/articles\/#organization\"},\"image\":{\"@id\":\"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/credevo.com\/articles\/wp-content\/uploads\/2017\/10\/acute_unilateral_vestibulopathy_clinical_trial_feasibility_credevo.jpg\",\"keywords\":[\"australia\",\"clinical trial feasibility\",\"TGA\"],\"articleSection\":[\"Clinical Development\",\"Feasibility\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/\",\"url\":\"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/\",\"name\":\"Acute Unilateral Vestibulopathy - A Clinical Trial Feasibility | Credevo Articles\",\"isPartOf\":{\"@id\":\"https:\/\/credevo.com\/articles\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/#primaryimage\"},\"image\":{\"@id\":\"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/#primaryimage\"},\"thumbnailUrl\":\"https:\/\/credevo.com\/articles\/wp-content\/uploads\/2017\/10\/acute_unilateral_vestibulopathy_clinical_trial_feasibility_credevo.jpg\",\"datePublished\":\"2017-09-11T04:41:19+00:00\",\"dateModified\":\"2021-09-20T10:32:01+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/#primaryimage\",\"url\":\"https:\/\/credevo.com\/articles\/wp-content\/uploads\/2017\/10\/acute_unilateral_vestibulopathy_clinical_trial_feasibility_credevo.jpg\",\"contentUrl\":\"https:\/\/credevo.com\/articles\/wp-content\/uploads\/2017\/10\/acute_unilateral_vestibulopathy_clinical_trial_feasibility_credevo.jpg\",\"width\":1920,\"height\":1028,\"caption\":\"acute_unilateral_vestibulopathy_clinical_trial_feasibility_credevo\"},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/credevo.com\/articles\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Acute Unilateral Vestibulopathy &#8211; A Clinical Trial Feasibility\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/credevo.com\/articles\/#website\",\"url\":\"https:\/\/credevo.com\/articles\/\",\"name\":\"Credevo\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/credevo.com\/articles\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/credevo.com\/articles\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/credevo.com\/articles\/#organization\",\"name\":\"Credevo Pte. Ltd.\",\"url\":\"https:\/\/credevo.com\/articles\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/credevo.com\/articles\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/credevo.com\/articles\/wp-content\/uploads\/2021\/04\/CREDEVO-HORIZONTAL.jpg\",\"contentUrl\":\"https:\/\/credevo.com\/articles\/wp-content\/uploads\/2021\/04\/CREDEVO-HORIZONTAL.jpg\",\"width\":320,\"height\":119,\"caption\":\"Credevo Pte. Ltd.\"},\"image\":{\"@id\":\"https:\/\/credevo.com\/articles\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/credevo\",\"https:\/\/x.com\/gocredevo\",\"https:\/\/www.instagram.com\/credevo_official\/\",\"https:\/\/www.linkedin.com\/company\/credevo\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/credevo.com\/articles\/#\/schema\/person\/eaf79e204cf3f6b11d8925cdd7adb3ed\",\"name\":\"Feasibility Team\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/credevo.com\/articles\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/0f5b3e164715f8b2e66af0b776460d63?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/0f5b3e164715f8b2e66af0b776460d63?s=96&d=mm&r=g\",\"caption\":\"Feasibility Team\"},\"sameAs\":[\"http:\/\/www.credevo.com\"],\"url\":\"https:\/\/credevo.com\/articles\/author\/fteam\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Acute Unilateral Vestibulopathy - A Clinical Trial Feasibility | Credevo Articles","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/","og_locale":"en_US","og_type":"article","og_title":"Acute Unilateral Vestibulopathy - A Clinical Trial Feasibility | Credevo Articles","og_description":"Acute vestibulopathy is characterized by an acute or subacute onset of vertigo, dizziness, or imbalance with or without ocular motor, sensory, postural or autonomic symptoms, and signs, and can last for seconds to up to several days. What is Acute Unilateral Vestibulopathy? Normal vestibular end organs generate an equal resting-firing frequency of the axons, which [&hellip;]","og_url":"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/","og_site_name":"Credevo Articles","article_publisher":"https:\/\/www.facebook.com\/credevo","article_published_time":"2017-09-11T04:41:19+00:00","article_modified_time":"2021-09-20T10:32:01+00:00","og_image":[{"width":1920,"height":1028,"url":"https:\/\/credevo.com\/articles\/wp-content\/uploads\/2017\/10\/acute_unilateral_vestibulopathy_clinical_trial_feasibility_credevo.jpg","type":"image\/jpeg"}],"author":"Feasibility Team","twitter_card":"summary_large_image","twitter_creator":"@gocredevo","twitter_site":"@gocredevo","twitter_misc":{"Written by":"Feasibility Team","Est. reading time":"4 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/#article","isPartOf":{"@id":"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/"},"author":{"name":"Feasibility Team","@id":"https:\/\/credevo.com\/articles\/#\/schema\/person\/eaf79e204cf3f6b11d8925cdd7adb3ed"},"headline":"Acute Unilateral Vestibulopathy &#8211; A Clinical Trial Feasibility","datePublished":"2017-09-11T04:41:19+00:00","dateModified":"2021-09-20T10:32:01+00:00","mainEntityOfPage":{"@id":"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/"},"wordCount":774,"publisher":{"@id":"https:\/\/credevo.com\/articles\/#organization"},"image":{"@id":"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/#primaryimage"},"thumbnailUrl":"https:\/\/credevo.com\/articles\/wp-content\/uploads\/2017\/10\/acute_unilateral_vestibulopathy_clinical_trial_feasibility_credevo.jpg","keywords":["australia","clinical trial feasibility","TGA"],"articleSection":["Clinical Development","Feasibility"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/","url":"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/","name":"Acute Unilateral Vestibulopathy - A Clinical Trial Feasibility | Credevo Articles","isPartOf":{"@id":"https:\/\/credevo.com\/articles\/#website"},"primaryImageOfPage":{"@id":"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/#primaryimage"},"image":{"@id":"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/#primaryimage"},"thumbnailUrl":"https:\/\/credevo.com\/articles\/wp-content\/uploads\/2017\/10\/acute_unilateral_vestibulopathy_clinical_trial_feasibility_credevo.jpg","datePublished":"2017-09-11T04:41:19+00:00","dateModified":"2021-09-20T10:32:01+00:00","breadcrumb":{"@id":"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/#primaryimage","url":"https:\/\/credevo.com\/articles\/wp-content\/uploads\/2017\/10\/acute_unilateral_vestibulopathy_clinical_trial_feasibility_credevo.jpg","contentUrl":"https:\/\/credevo.com\/articles\/wp-content\/uploads\/2017\/10\/acute_unilateral_vestibulopathy_clinical_trial_feasibility_credevo.jpg","width":1920,"height":1028,"caption":"acute_unilateral_vestibulopathy_clinical_trial_feasibility_credevo"},{"@type":"BreadcrumbList","@id":"https:\/\/credevo.com\/articles\/2017\/09\/11\/acute-unilateral-vestibulopathy-a-clinical-trial-feasibility\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/credevo.com\/articles\/"},{"@type":"ListItem","position":2,"name":"Acute Unilateral Vestibulopathy &#8211; A Clinical Trial Feasibility"}]},{"@type":"WebSite","@id":"https:\/\/credevo.com\/articles\/#website","url":"https:\/\/credevo.com\/articles\/","name":"Credevo","description":"","publisher":{"@id":"https:\/\/credevo.com\/articles\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/credevo.com\/articles\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/credevo.com\/articles\/#organization","name":"Credevo Pte. Ltd.","url":"https:\/\/credevo.com\/articles\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/credevo.com\/articles\/#\/schema\/logo\/image\/","url":"https:\/\/credevo.com\/articles\/wp-content\/uploads\/2021\/04\/CREDEVO-HORIZONTAL.jpg","contentUrl":"https:\/\/credevo.com\/articles\/wp-content\/uploads\/2021\/04\/CREDEVO-HORIZONTAL.jpg","width":320,"height":119,"caption":"Credevo Pte. Ltd."},"image":{"@id":"https:\/\/credevo.com\/articles\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/credevo","https:\/\/x.com\/gocredevo","https:\/\/www.instagram.com\/credevo_official\/","https:\/\/www.linkedin.com\/company\/credevo"]},{"@type":"Person","@id":"https:\/\/credevo.com\/articles\/#\/schema\/person\/eaf79e204cf3f6b11d8925cdd7adb3ed","name":"Feasibility Team","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/credevo.com\/articles\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/0f5b3e164715f8b2e66af0b776460d63?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/0f5b3e164715f8b2e66af0b776460d63?s=96&d=mm&r=g","caption":"Feasibility Team"},"sameAs":["http:\/\/www.credevo.com"],"url":"https:\/\/credevo.com\/articles\/author\/fteam\/"}]}},"_links":{"self":[{"href":"https:\/\/credevo.com\/articles\/wp-json\/wp\/v2\/posts\/267"}],"collection":[{"href":"https:\/\/credevo.com\/articles\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/credevo.com\/articles\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/credevo.com\/articles\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/credevo.com\/articles\/wp-json\/wp\/v2\/comments?post=267"}],"version-history":[{"count":24,"href":"https:\/\/credevo.com\/articles\/wp-json\/wp\/v2\/posts\/267\/revisions"}],"predecessor-version":[{"id":6491,"href":"https:\/\/credevo.com\/articles\/wp-json\/wp\/v2\/posts\/267\/revisions\/6491"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/credevo.com\/articles\/wp-json\/wp\/v2\/media\/287"}],"wp:attachment":[{"href":"https:\/\/credevo.com\/articles\/wp-json\/wp\/v2\/media?parent=267"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/credevo.com\/articles\/wp-json\/wp\/v2\/categories?post=267"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/credevo.com\/articles\/wp-json\/wp\/v2\/tags?post=267"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}